Tebilon
Brand names,
Tebilon
Analogs
Tebilon
Brand Names Mixture
Tebilon
Chemical_Formula
C19H24N2O3
Tebilon
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tebilon
fda sheet
Tebilon
msds (material safety sheet)
Tebilon
Synthesis Reference
No information avaliable
Tebilon
Molecular Weight
328.406 g/mol
Tebilon
Melting Point
195-196 oC
Tebilon
H2O Solubility
20 mg/ml (HCl salt)
Tebilon
State
Solid
Tebilon
LogP
2.868
Tebilon
Dosage Forms
Liquid; Tablet
Tebilon
Indication
For the management of hypertension.
Tebilon
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tebilon
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tebilon
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tebilon
Patient Information
Tebilon
Organisms Affected
Humans and other mammals