Mybasan
Brand names,
Mybasan
Analogs
Mybasan
Brand Names Mixture
Mybasan
Chemical_Formula
C19H24N2O3
Mybasan
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Mybasan
fda sheet
Mybasan
msds (material safety sheet)
Mybasan
Synthesis Reference
No information avaliable
Mybasan
Molecular Weight
328.406 g/mol
Mybasan
Melting Point
195-196 oC
Mybasan
H2O Solubility
20 mg/ml (HCl salt)
Mybasan
State
Solid
Mybasan
LogP
2.868
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Dosage Forms
Liquid; Tablet
Mybasan
Indication
For the management of hypertension.
Mybasan
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Mybasan
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Mybasan
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Mybasan
Patient Information
Mybasan
Organisms Affected
Humans and other mammals