Isozyd
Brand names,
Isozyd
Analogs
Isozyd
Brand Names Mixture
Isozyd
Chemical_Formula
C19H24N2O3
Isozyd
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Isozyd
fda sheet
Isozyd
msds (material safety sheet)
Isozyd
Synthesis Reference
No information avaliable
Isozyd
Molecular Weight
328.406 g/mol
Isozyd
Melting Point
195-196 oC
Isozyd
H2O Solubility
20 mg/ml (HCl salt)
Isozyd
State
Solid
Isozyd
LogP
2.868
Isozyd
Dosage Forms
Liquid; Tablet
Isozyd
Indication
For the management of hypertension.
Isozyd
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Isozyd
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Isozyd
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Isozyd
Patient Information
Isozyd
Organisms Affected
Humans and other mammals