Idrazil
Brand names,
Idrazil
Analogs
Idrazil
Brand Names Mixture
Idrazil
Chemical_Formula
C19H24N2O3
Idrazil
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Idrazil
fda sheet
Idrazil
msds (material safety sheet)
Idrazil
Synthesis Reference
No information avaliable
Idrazil
Molecular Weight
328.406 g/mol
Idrazil
Melting Point
195-196 oC
Idrazil
H2O Solubility
20 mg/ml (HCl salt)
Idrazil
State
Solid
Idrazil
LogP
2.868
Idrazil
Dosage Forms
Liquid; Tablet
Idrazil
Indication
For the management of hypertension.
Idrazil
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Idrazil
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Idrazil
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Idrazil
Patient Information
Idrazil
Organisms Affected
Humans and other mammals