Cortinazine
Brand names,
Cortinazine
Analogs
Cortinazine
Brand Names Mixture
Cortinazine
Chemical_Formula
C19H24N2O3
Cortinazine
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Cortinazine
fda sheet
Cortinazine
msds (material safety sheet)
Cortinazine
Synthesis Reference
No information avaliable
Cortinazine
Molecular Weight
328.406 g/mol
Cortinazine
Melting Point
195-196 oC
Cortinazine
H2O Solubility
20 mg/ml (HCl salt)
Cortinazine
State
Solid
Cortinazine
LogP
2.868
Cortinazine
Dosage Forms
Liquid; Tablet
Cortinazine
Indication
For the management of hypertension.
Cortinazine
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Cortinazine
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Cortinazine
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Cortinazine
Patient Information
Cortinazine
Organisms Affected
Humans and other mammals