Neo-Tizide
Brand names,
Neo-Tizide
Analogs
Neo-Tizide
Brand Names Mixture
Neo-Tizide
Chemical_Formula
C19H24N2O3
Neo-Tizide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Neo-Tizide
fda sheet
Neo-Tizide
msds (material safety sheet)
Neo-Tizide
Synthesis Reference
No information avaliable
Neo-Tizide
Molecular Weight
328.406 g/mol
Neo-Tizide
Melting Point
195-196 oC
Neo-Tizide
H2O Solubility
20 mg/ml (HCl salt)
Neo-Tizide
State
Solid
Neo-Tizide
LogP
2.868
Neo-Tizide
Dosage Forms
Liquid; Tablet
Neo-Tizide
Indication
For the management of hypertension.
Neo-Tizide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Neo-Tizide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Neo-Tizide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Neo-Tizide
Patient Information
Neo-Tizide
Organisms Affected
Humans and other mammals