Tebenic
Brand names,
Tebenic
Analogs
Tebenic
Brand Names Mixture
Tebenic
Chemical_Formula
C19H24N2O3
Tebenic
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tebenic
fda sheet
Tebenic
msds (material safety sheet)
Tebenic
Synthesis Reference
No information avaliable
Tebenic
Molecular Weight
328.406 g/mol
Tebenic
Melting Point
195-196 oC
Tebenic
H2O Solubility
20 mg/ml (HCl salt)
Tebenic
State
Solid
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LogP
2.868
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Dosage Forms
Liquid; Tablet
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Indication
For the management of hypertension.
Tebenic
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tebenic
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tebenic
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tebenic
Patient Information
Tebenic
Organisms Affected
Humans and other mammals