Pyrizidin
Brand names,
Pyrizidin
Analogs
Pyrizidin
Brand Names Mixture
Pyrizidin
Chemical_Formula
C19H24N2O3
Pyrizidin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Pyrizidin
fda sheet
Pyrizidin
msds (material safety sheet)
Pyrizidin
Synthesis Reference
No information avaliable
Pyrizidin
Molecular Weight
328.406 g/mol
Pyrizidin
Melting Point
195-196 oC
Pyrizidin
H2O Solubility
20 mg/ml (HCl salt)
Pyrizidin
State
Solid
Pyrizidin
LogP
2.868
Pyrizidin
Dosage Forms
Liquid; Tablet
Pyrizidin
Indication
For the management of hypertension.
Pyrizidin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Pyrizidin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Pyrizidin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Pyrizidin
Patient Information
Pyrizidin
Organisms Affected
Humans and other mammals