Cedin
Brand names,
Cedin
Analogs
Cedin
Brand Names Mixture
Cedin
Chemical_Formula
C19H24N2O3
Cedin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Cedin
fda sheet
Cedin
msds (material safety sheet)
Cedin
Synthesis Reference
No information avaliable
Cedin
Molecular Weight
328.406 g/mol
Cedin
Melting Point
195-196 oC
Cedin
H2O Solubility
20 mg/ml (HCl salt)
Cedin
State
Solid
Cedin
LogP
2.868
Cedin
Dosage Forms
Liquid; Tablet
Cedin
Indication
For the management of hypertension.
Cedin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Cedin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Cedin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Cedin
Patient Information
Cedin
Organisms Affected
Humans and other mammals