Tubeco
Brand names,
Tubeco
Analogs
Tubeco
Brand Names Mixture
Tubeco
Chemical_Formula
C19H24N2O3
Tubeco
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tubeco
fda sheet
Tubeco
msds (material safety sheet)
Tubeco
Synthesis Reference
No information avaliable
Tubeco
Molecular Weight
328.406 g/mol
Tubeco
Melting Point
195-196 oC
Tubeco
H2O Solubility
20 mg/ml (HCl salt)
Tubeco
State
Solid
Tubeco
LogP
2.868
Tubeco
Dosage Forms
Liquid; Tablet
Tubeco
Indication
For the management of hypertension.
Tubeco
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tubeco
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tubeco
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tubeco
Patient Information
Tubeco
Organisms Affected
Humans and other mammals