Nicazide
Brand names,
Nicazide
Analogs
Nicazide
Brand Names Mixture
Nicazide
Chemical_Formula
C19H24N2O3
Nicazide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Nicazide
fda sheet
Nicazide
msds (material safety sheet)
Nicazide
Synthesis Reference
No information avaliable
Nicazide
Molecular Weight
328.406 g/mol
Nicazide
Melting Point
195-196 oC
Nicazide
H2O Solubility
20 mg/ml (HCl salt)
Nicazide
State
Solid
Nicazide
LogP
2.868
Nicazide
Dosage Forms
Liquid; Tablet
Nicazide
Indication
For the management of hypertension.
Nicazide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Nicazide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Nicazide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Nicazide
Patient Information
Nicazide
Organisms Affected
Humans and other mammals