Tubilysin
Brand names,
Tubilysin
Analogs
Tubilysin
Brand Names Mixture
Tubilysin
Chemical_Formula
C19H24N2O3
Tubilysin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tubilysin
fda sheet
Tubilysin
msds (material safety sheet)
Tubilysin
Synthesis Reference
No information avaliable
Tubilysin
Molecular Weight
328.406 g/mol
Tubilysin
Melting Point
195-196 oC
Tubilysin
H2O Solubility
20 mg/ml (HCl salt)
Tubilysin
State
Solid
Tubilysin
LogP
2.868
Tubilysin
Dosage Forms
Liquid; Tablet
Tubilysin
Indication
For the management of hypertension.
Tubilysin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tubilysin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tubilysin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tubilysin
Patient Information
Tubilysin
Organisms Affected
Humans and other mammals