Vazadrine
Brand names,
Vazadrine
Analogs
Vazadrine
Brand Names Mixture
Vazadrine
Chemical_Formula
C19H24N2O3
Vazadrine
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Vazadrine
fda sheet
Vazadrine
msds (material safety sheet)
Vazadrine
Synthesis Reference
No information avaliable
Vazadrine
Molecular Weight
328.406 g/mol
Vazadrine
Melting Point
195-196 oC
Vazadrine
H2O Solubility
20 mg/ml (HCl salt)
Vazadrine
State
Solid
Vazadrine
LogP
2.868
Vazadrine
Dosage Forms
Liquid; Tablet
Vazadrine
Indication
For the management of hypertension.
Vazadrine
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Vazadrine
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Vazadrine
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Vazadrine
Patient Information
Vazadrine
Organisms Affected
Humans and other mammals