Isocidene
Brand names,
Isocidene
Analogs
Isocidene
Brand Names Mixture
Isocidene
Chemical_Formula
C19H24N2O3
Isocidene
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Isocidene
fda sheet
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msds (material safety sheet)
Isocidene
Synthesis Reference
No information avaliable
Isocidene
Molecular Weight
328.406 g/mol
Isocidene
Melting Point
195-196 oC
Isocidene
H2O Solubility
20 mg/ml (HCl salt)
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State
Solid
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LogP
2.868
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Dosage Forms
Liquid; Tablet
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Indication
For the management of hypertension.
Isocidene
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Isocidene
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
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side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
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Patient Information
Isocidene
Organisms Affected
Humans and other mammals