Hyzyd
Brand names,
Hyzyd
Analogs
Hyzyd
Brand Names Mixture
Hyzyd
Chemical_Formula
C19H24N2O3
Hyzyd
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Hyzyd
fda sheet
Hyzyd
msds (material safety sheet)
Hyzyd
Synthesis Reference
No information avaliable
Hyzyd
Molecular Weight
328.406 g/mol
Hyzyd
Melting Point
195-196 oC
Hyzyd
H2O Solubility
20 mg/ml (HCl salt)
Hyzyd
State
Solid
Hyzyd
LogP
2.868
Hyzyd
Dosage Forms
Liquid; Tablet
Hyzyd
Indication
For the management of hypertension.
Hyzyd
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Hyzyd
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Hyzyd
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Hyzyd
Patient Information
Hyzyd
Organisms Affected
Humans and other mammals