Armacide
Brand names,
Armacide
Analogs
Armacide
Brand Names Mixture
Armacide
Chemical_Formula
C19H24N2O3
Armacide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Armacide
fda sheet
Armacide
msds (material safety sheet)
Armacide
Synthesis Reference
No information avaliable
Armacide
Molecular Weight
328.406 g/mol
Armacide
Melting Point
195-196 oC
Armacide
H2O Solubility
20 mg/ml (HCl salt)
Armacide
State
Solid
Armacide
LogP
2.868
Armacide
Dosage Forms
Liquid; Tablet
Armacide
Indication
For the management of hypertension.
Armacide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Armacide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Armacide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Armacide
Patient Information
Armacide
Organisms Affected
Humans and other mammals