Isoniazide
Brand names,
Isoniazide
Analogs
Isoniazide
Brand Names Mixture
Isoniazide
Chemical_Formula
C19H24N2O3
Isoniazide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Isoniazide
fda sheet
Isoniazide
msds (material safety sheet)
Isoniazide
Synthesis Reference
No information avaliable
Isoniazide
Molecular Weight
328.406 g/mol
Isoniazide
Melting Point
195-196 oC
Isoniazide
H2O Solubility
20 mg/ml (HCl salt)
Isoniazide
State
Solid
Isoniazide
LogP
2.868
Isoniazide
Dosage Forms
Liquid; Tablet
Isoniazide
Indication
For the management of hypertension.
Isoniazide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Isoniazide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Isoniazide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Isoniazide
Patient Information
Isoniazide
Organisms Affected
Humans and other mammals