Ido-tebin
Brand names,
Ido-tebin
Analogs
Ido-tebin
Brand Names Mixture
Ido-tebin
Chemical_Formula
C19H24N2O3
Ido-tebin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Ido-tebin
fda sheet
Ido-tebin
msds (material safety sheet)
Ido-tebin
Synthesis Reference
No information avaliable
Ido-tebin
Molecular Weight
328.406 g/mol
Ido-tebin
Melting Point
195-196 oC
Ido-tebin
H2O Solubility
20 mg/ml (HCl salt)
Ido-tebin
State
Solid
Ido-tebin
LogP
2.868
Ido-tebin
Dosage Forms
Liquid; Tablet
Ido-tebin
Indication
For the management of hypertension.
Ido-tebin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Ido-tebin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Ido-tebin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Ido-tebin
Patient Information
Ido-tebin
Organisms Affected
Humans and other mammals