Sauterazid
Brand names,
Sauterazid
Analogs
Sauterazid
Brand Names Mixture
Sauterazid
Chemical_Formula
C19H24N2O3
Sauterazid
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Sauterazid
fda sheet
Sauterazid
msds (material safety sheet)
Sauterazid
Synthesis Reference
No information avaliable
Sauterazid
Molecular Weight
328.406 g/mol
Sauterazid
Melting Point
195-196 oC
Sauterazid
H2O Solubility
20 mg/ml (HCl salt)
Sauterazid
State
Solid
Sauterazid
LogP
2.868
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Dosage Forms
Liquid; Tablet
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Indication
For the management of hypertension.
Sauterazid
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Sauterazid
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Sauterazid
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Sauterazid
Patient Information
Sauterazid
Organisms Affected
Humans and other mammals