Cemidon
Brand names,
Cemidon
Analogs
Cemidon
Brand Names Mixture
Cemidon
Chemical_Formula
C19H24N2O3
Cemidon
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Cemidon
fda sheet
Cemidon
msds (material safety sheet)
Cemidon
Synthesis Reference
No information avaliable
Cemidon
Molecular Weight
328.406 g/mol
Cemidon
Melting Point
195-196 oC
Cemidon
H2O Solubility
20 mg/ml (HCl salt)
Cemidon
State
Solid
Cemidon
LogP
2.868
Cemidon
Dosage Forms
Liquid; Tablet
Cemidon
Indication
For the management of hypertension.
Cemidon
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Cemidon
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Cemidon
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Cemidon
Patient Information
Cemidon
Organisms Affected
Humans and other mammals