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Nicotibine Brand names, Nicotibine Analogs

Nicotibine Brand Names Mixture

  • No information avaliable

Nicotibine Chemical_Formula

C19H24N2O3

Nicotibine RX_link

http://www.rxlist.com/cgi/generic2/labet.htm

Nicotibine fda sheet

Nicotibine FDA

Nicotibine msds (material safety sheet)

Nicotibine MSDS

Nicotibine Synthesis Reference

No information avaliable

Nicotibine Molecular Weight

328.406 g/mol

Nicotibine Melting Point

195-196 oC

Nicotibine H2O Solubility

20 mg/ml (HCl salt)

Nicotibine State

Solid

Nicotibine LogP

2.868

Nicotibine Dosage Forms

Liquid; Tablet

Nicotibine Indication

For the management of hypertension.

Nicotibine Pharmacology

Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.

Nicotibine Absorption

Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.

Nicotibine side effects and Toxicity

LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue

Nicotibine Patient Information

Nicotibine Organisms Affected

Humans and other mammals