Dinacrin
Brand names,
Dinacrin
Analogs
Dinacrin
Brand Names Mixture
Dinacrin
Chemical_Formula
C19H24N2O3
Dinacrin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Dinacrin
fda sheet
Dinacrin
msds (material safety sheet)
Dinacrin
Synthesis Reference
No information avaliable
Dinacrin
Molecular Weight
328.406 g/mol
Dinacrin
Melting Point
195-196 oC
Dinacrin
H2O Solubility
20 mg/ml (HCl salt)
Dinacrin
State
Solid
Dinacrin
LogP
2.868
Dinacrin
Dosage Forms
Liquid; Tablet
Dinacrin
Indication
For the management of hypertension.
Dinacrin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Dinacrin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Dinacrin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Dinacrin
Patient Information
Dinacrin
Organisms Affected
Humans and other mammals