Hidrasonil
Brand names,
Hidrasonil
Analogs
Hidrasonil
Brand Names Mixture
Hidrasonil
Chemical_Formula
C19H24N2O3
Hidrasonil
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Hidrasonil
fda sheet
Hidrasonil
msds (material safety sheet)
Hidrasonil
Synthesis Reference
No information avaliable
Hidrasonil
Molecular Weight
328.406 g/mol
Hidrasonil
Melting Point
195-196 oC
Hidrasonil
H2O Solubility
20 mg/ml (HCl salt)
Hidrasonil
State
Solid
Hidrasonil
LogP
2.868
Hidrasonil
Dosage Forms
Liquid; Tablet
Hidrasonil
Indication
For the management of hypertension.
Hidrasonil
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Hidrasonil
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Hidrasonil
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Hidrasonil
Patient Information
Hidrasonil
Organisms Affected
Humans and other mammals