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Defonin Brand names, Defonin Analogs

Defonin Brand Names Mixture

  • No information avaliable

Defonin Chemical_Formula

C19H24N2O3

Defonin RX_link

http://www.rxlist.com/cgi/generic2/labet.htm

Defonin fda sheet

Defonin FDA

Defonin msds (material safety sheet)

Defonin MSDS

Defonin Synthesis Reference

No information avaliable

Defonin Molecular Weight

328.406 g/mol

Defonin Melting Point

195-196 oC

Defonin H2O Solubility

20 mg/ml (HCl salt)

Defonin State

Solid

Defonin LogP

2.868

Defonin Dosage Forms

Liquid; Tablet

Defonin Indication

For the management of hypertension.

Defonin Pharmacology

Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.

Defonin Absorption

Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.

Defonin side effects and Toxicity

LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue

Defonin Patient Information

Defonin Organisms Affected

Humans and other mammals