Sanohidrazina
Brand names,
Sanohidrazina
Analogs
Sanohidrazina
Brand Names Mixture
Sanohidrazina
Chemical_Formula
C19H24N2O3
Sanohidrazina
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Sanohidrazina
fda sheet
Sanohidrazina
msds (material safety sheet)
Sanohidrazina
Synthesis Reference
No information avaliable
Sanohidrazina
Molecular Weight
328.406 g/mol
Sanohidrazina
Melting Point
195-196 oC
Sanohidrazina
H2O Solubility
20 mg/ml (HCl salt)
Sanohidrazina
State
Solid
Sanohidrazina
LogP
2.868
Sanohidrazina
Dosage Forms
Liquid; Tablet
Sanohidrazina
Indication
For the management of hypertension.
Sanohidrazina
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Sanohidrazina
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Sanohidrazina
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Sanohidrazina
Patient Information
Sanohidrazina
Organisms Affected
Humans and other mammals