Hyozid
Brand names,
Hyozid
Analogs
Hyozid
Brand Names Mixture
Hyozid
Chemical_Formula
C19H24N2O3
Hyozid
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Hyozid
fda sheet
Hyozid
msds (material safety sheet)
Hyozid
Synthesis Reference
No information avaliable
Hyozid
Molecular Weight
328.406 g/mol
Hyozid
Melting Point
195-196 oC
Hyozid
H2O Solubility
20 mg/ml (HCl salt)
Hyozid
State
Solid
Hyozid
LogP
2.868
Hyozid
Dosage Forms
Liquid; Tablet
Hyozid
Indication
For the management of hypertension.
Hyozid
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Hyozid
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Hyozid
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Hyozid
Patient Information
Hyozid
Organisms Affected
Humans and other mammals