Isoniton
Brand names,
Isoniton
Analogs
Isoniton
Brand Names Mixture
Isoniton
Chemical_Formula
C19H24N2O3
Isoniton
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Isoniton
fda sheet
Isoniton
msds (material safety sheet)
Isoniton
Synthesis Reference
No information avaliable
Isoniton
Molecular Weight
328.406 g/mol
Isoniton
Melting Point
195-196 oC
Isoniton
H2O Solubility
20 mg/ml (HCl salt)
Isoniton
State
Solid
Isoniton
LogP
2.868
Isoniton
Dosage Forms
Liquid; Tablet
Isoniton
Indication
For the management of hypertension.
Isoniton
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Isoniton
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Isoniton
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Isoniton
Patient Information
Isoniton
Organisms Affected
Humans and other mammals