Tubecotubercid
Brand names,
Tubecotubercid
Analogs
Tubecotubercid
Brand Names Mixture
Tubecotubercid
Chemical_Formula
C19H24N2O3
Tubecotubercid
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tubecotubercid
fda sheet
Tubecotubercid
msds (material safety sheet)
Tubecotubercid
Synthesis Reference
No information avaliable
Tubecotubercid
Molecular Weight
328.406 g/mol
Tubecotubercid
Melting Point
195-196 oC
Tubecotubercid
H2O Solubility
20 mg/ml (HCl salt)
Tubecotubercid
State
Solid
Tubecotubercid
LogP
2.868
Tubecotubercid
Dosage Forms
Liquid; Tablet
Tubecotubercid
Indication
For the management of hypertension.
Tubecotubercid
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tubecotubercid
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tubecotubercid
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tubecotubercid
Patient Information
Tubecotubercid
Organisms Affected
Humans and other mammals