Tebecid
Brand names,
Tebecid
Analogs
Tebecid
Brand Names Mixture
Tebecid
Chemical_Formula
C19H24N2O3
Tebecid
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tebecid
fda sheet
Tebecid
msds (material safety sheet)
Tebecid
Synthesis Reference
No information avaliable
Tebecid
Molecular Weight
328.406 g/mol
Tebecid
Melting Point
195-196 oC
Tebecid
H2O Solubility
20 mg/ml (HCl salt)
Tebecid
State
Solid
Tebecid
LogP
2.868
Tebecid
Dosage Forms
Liquid; Tablet
Tebecid
Indication
For the management of hypertension.
Tebecid
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tebecid
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tebecid
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tebecid
Patient Information
Tebecid
Organisms Affected
Humans and other mammals