Isozide
Brand names,
Isozide
Analogs
Isozide
Brand Names Mixture
Isozide
Chemical_Formula
C19H24N2O3
Isozide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Isozide
fda sheet
Isozide
msds (material safety sheet)
Isozide
Synthesis Reference
No information avaliable
Isozide
Molecular Weight
328.406 g/mol
Isozide
Melting Point
195-196 oC
Isozide
H2O Solubility
20 mg/ml (HCl salt)
Isozide
State
Solid
Isozide
LogP
2.868
Isozide
Dosage Forms
Liquid; Tablet
Isozide
Indication
For the management of hypertension.
Isozide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Isozide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Isozide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Isozide
Patient Information
Isozide
Organisms Affected
Humans and other mammals