Andrazide
Brand names,
Andrazide
Analogs
Andrazide
Brand Names Mixture
Andrazide
Chemical_Formula
C19H24N2O3
Andrazide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Andrazide
fda sheet
Andrazide
msds (material safety sheet)
Andrazide
Synthesis Reference
No information avaliable
Andrazide
Molecular Weight
328.406 g/mol
Andrazide
Melting Point
195-196 oC
Andrazide
H2O Solubility
20 mg/ml (HCl salt)
Andrazide
State
Solid
Andrazide
LogP
2.868
Andrazide
Dosage Forms
Liquid; Tablet
Andrazide
Indication
For the management of hypertension.
Andrazide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Andrazide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Andrazide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Andrazide
Patient Information
Andrazide
Organisms Affected
Humans and other mammals