Pyridicin
Brand names,
Pyridicin
Analogs
Pyridicin
Brand Names Mixture
Pyridicin
Chemical_Formula
C19H24N2O3
Pyridicin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Pyridicin
fda sheet
Pyridicin
msds (material safety sheet)
Pyridicin
Synthesis Reference
No information avaliable
Pyridicin
Molecular Weight
328.406 g/mol
Pyridicin
Melting Point
195-196 oC
Pyridicin
H2O Solubility
20 mg/ml (HCl salt)
Pyridicin
State
Solid
Pyridicin
LogP
2.868
Pyridicin
Dosage Forms
Liquid; Tablet
Pyridicin
Indication
For the management of hypertension.
Pyridicin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Pyridicin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Pyridicin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Pyridicin
Patient Information
Pyridicin
Organisms Affected
Humans and other mammals