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Atcotibine Brand names, Atcotibine Analogs

Atcotibine Brand Names Mixture

  • No information avaliable

Atcotibine Chemical_Formula

C19H24N2O3

Atcotibine RX_link

http://www.rxlist.com/cgi/generic2/labet.htm

Atcotibine fda sheet

Atcotibine FDA

Atcotibine msds (material safety sheet)

Atcotibine MSDS

Atcotibine Synthesis Reference

No information avaliable

Atcotibine Molecular Weight

328.406 g/mol

Atcotibine Melting Point

195-196 oC

Atcotibine H2O Solubility

20 mg/ml (HCl salt)

Atcotibine State

Solid

Atcotibine LogP

2.868

Atcotibine Dosage Forms

Liquid; Tablet

Atcotibine Indication

For the management of hypertension.

Atcotibine Pharmacology

Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.

Atcotibine Absorption

Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.

Atcotibine side effects and Toxicity

LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue

Atcotibine Patient Information

Atcotibine Organisms Affected

Humans and other mammals