Unicozyde
Brand names,
Unicozyde
Analogs
Unicozyde
Brand Names Mixture
Unicozyde
Chemical_Formula
C19H24N2O3
Unicozyde
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Unicozyde
fda sheet
Unicozyde
msds (material safety sheet)
Unicozyde
Synthesis Reference
No information avaliable
Unicozyde
Molecular Weight
328.406 g/mol
Unicozyde
Melting Point
195-196 oC
Unicozyde
H2O Solubility
20 mg/ml (HCl salt)
Unicozyde
State
Solid
Unicozyde
LogP
2.868
Unicozyde
Dosage Forms
Liquid; Tablet
Unicozyde
Indication
For the management of hypertension.
Unicozyde
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Unicozyde
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Unicozyde
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Unicozyde
Patient Information
Unicozyde
Organisms Affected
Humans and other mammals