Tuberian
Brand names,
Tuberian
Analogs
Tuberian
Brand Names Mixture
Tuberian
Chemical_Formula
C19H24N2O3
Tuberian
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tuberian
fda sheet
Tuberian
msds (material safety sheet)
Tuberian
Synthesis Reference
No information avaliable
Tuberian
Molecular Weight
328.406 g/mol
Tuberian
Melting Point
195-196 oC
Tuberian
H2O Solubility
20 mg/ml (HCl salt)
Tuberian
State
Solid
Tuberian
LogP
2.868
Tuberian
Dosage Forms
Liquid; Tablet
Tuberian
Indication
For the management of hypertension.
Tuberian
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tuberian
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tuberian
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tuberian
Patient Information
Tuberian
Organisms Affected
Humans and other mammals