Robiselin
Brand names,
Robiselin
Analogs
Robiselin
Brand Names Mixture
Robiselin
Chemical_Formula
C19H24N2O3
Robiselin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Robiselin
fda sheet
Robiselin
msds (material safety sheet)
Robiselin
Synthesis Reference
No information avaliable
Robiselin
Molecular Weight
328.406 g/mol
Robiselin
Melting Point
195-196 oC
Robiselin
H2O Solubility
20 mg/ml (HCl salt)
Robiselin
State
Solid
Robiselin
LogP
2.868
Robiselin
Dosage Forms
Liquid; Tablet
Robiselin
Indication
For the management of hypertension.
Robiselin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Robiselin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Robiselin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Robiselin
Patient Information
Robiselin
Organisms Affected
Humans and other mammals