Tubazide
Brand names,
Tubazide
Analogs
Tubazide
Brand Names Mixture
Tubazide
Chemical_Formula
C19H24N2O3
Tubazide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tubazide
fda sheet
Tubazide
msds (material safety sheet)
Tubazide
Synthesis Reference
No information avaliable
Tubazide
Molecular Weight
328.406 g/mol
Tubazide
Melting Point
195-196 oC
Tubazide
H2O Solubility
20 mg/ml (HCl salt)
Tubazide
State
Solid
Tubazide
LogP
2.868
Tubazide
Dosage Forms
Liquid; Tablet
Tubazide
Indication
For the management of hypertension.
Tubazide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tubazide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tubazide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tubazide
Patient Information
Tubazide
Organisms Affected
Humans and other mammals