Pycazide
Brand names,
Pycazide
Analogs
Pycazide
Brand Names Mixture
Pycazide
Chemical_Formula
C19H24N2O3
Pycazide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Pycazide
fda sheet
Pycazide
msds (material safety sheet)
Pycazide
Synthesis Reference
No information avaliable
Pycazide
Molecular Weight
328.406 g/mol
Pycazide
Melting Point
195-196 oC
Pycazide
H2O Solubility
20 mg/ml (HCl salt)
Pycazide
State
Solid
Pycazide
LogP
2.868
Pycazide
Dosage Forms
Liquid; Tablet
Pycazide
Indication
For the management of hypertension.
Pycazide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Pycazide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Pycazide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Pycazide
Patient Information
Pycazide
Organisms Affected
Humans and other mammals