Zinadon
Brand names,
Zinadon
Analogs
Zinadon
Brand Names Mixture
Zinadon
Chemical_Formula
C19H24N2O3
Zinadon
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Zinadon
fda sheet
Zinadon
msds (material safety sheet)
Zinadon
Synthesis Reference
No information avaliable
Zinadon
Molecular Weight
328.406 g/mol
Zinadon
Melting Point
195-196 oC
Zinadon
H2O Solubility
20 mg/ml (HCl salt)
Zinadon
State
Solid
Zinadon
LogP
2.868
Zinadon
Dosage Forms
Liquid; Tablet
Zinadon
Indication
For the management of hypertension.
Zinadon
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Zinadon
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Zinadon
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Zinadon
Patient Information
Zinadon
Organisms Affected
Humans and other mammals