Robisellin
Brand names,
Robisellin
Analogs
Robisellin
Brand Names Mixture
Robisellin
Chemical_Formula
C19H24N2O3
Robisellin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Robisellin
fda sheet
Robisellin
msds (material safety sheet)
Robisellin
Synthesis Reference
No information avaliable
Robisellin
Molecular Weight
328.406 g/mol
Robisellin
Melting Point
195-196 oC
Robisellin
H2O Solubility
20 mg/ml (HCl salt)
Robisellin
State
Solid
Robisellin
LogP
2.868
Robisellin
Dosage Forms
Liquid; Tablet
Robisellin
Indication
For the management of hypertension.
Robisellin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Robisellin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Robisellin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Robisellin
Patient Information
Robisellin
Organisms Affected
Humans and other mammals