Tubomel
Brand names,
Tubomel
Analogs
Tubomel
Brand Names Mixture
Tubomel
Chemical_Formula
C19H24N2O3
Tubomel
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tubomel
fda sheet
Tubomel
msds (material safety sheet)
Tubomel
Synthesis Reference
No information avaliable
Tubomel
Molecular Weight
328.406 g/mol
Tubomel
Melting Point
195-196 oC
Tubomel
H2O Solubility
20 mg/ml (HCl salt)
Tubomel
State
Solid
Tubomel
LogP
2.868
Tubomel
Dosage Forms
Liquid; Tablet
Tubomel
Indication
For the management of hypertension.
Tubomel
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tubomel
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tubomel
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tubomel
Patient Information
Tubomel
Organisms Affected
Humans and other mammals