Sauterzid
Brand names,
Sauterzid
Analogs
Sauterzid
Brand Names Mixture
Sauterzid
Chemical_Formula
C19H24N2O3
Sauterzid
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
Sauterzid
Molecular Weight
328.406 g/mol
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Melting Point
195-196 oC
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H2O Solubility
20 mg/ml (HCl salt)
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State
Solid
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LogP
2.868
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Dosage Forms
Liquid; Tablet
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Indication
For the management of hypertension.
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Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Sauterzid
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
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side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
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Patient Information
Sauterzid
Organisms Affected
Humans and other mammals