Evalon
Brand names,
Evalon
Analogs
Evalon
Brand Names Mixture
Evalon
Chemical_Formula
C19H24N2O3
Evalon
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Evalon
fda sheet
Evalon
msds (material safety sheet)
Evalon
Synthesis Reference
No information avaliable
Evalon
Molecular Weight
328.406 g/mol
Evalon
Melting Point
195-196 oC
Evalon
H2O Solubility
20 mg/ml (HCl salt)
Evalon
State
Solid
Evalon
LogP
2.868
Evalon
Dosage Forms
Liquid; Tablet
Evalon
Indication
For the management of hypertension.
Evalon
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Evalon
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Evalon
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Evalon
Patient Information
Evalon
Organisms Affected
Humans and other mammals