Bacillin
Brand names,
Bacillin
Analogs
Bacillin
Brand Names Mixture
Bacillin
Chemical_Formula
C19H24N2O3
Bacillin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Bacillin
fda sheet
Bacillin
msds (material safety sheet)
Bacillin
Synthesis Reference
No information avaliable
Bacillin
Molecular Weight
328.406 g/mol
Bacillin
Melting Point
195-196 oC
Bacillin
H2O Solubility
20 mg/ml (HCl salt)
Bacillin
State
Solid
Bacillin
LogP
2.868
Bacillin
Dosage Forms
Liquid; Tablet
Bacillin
Indication
For the management of hypertension.
Bacillin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Bacillin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Bacillin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Bacillin
Patient Information
Bacillin
Organisms Affected
Humans and other mammals