Antimicina
Brand names,
Antimicina
Analogs
Antimicina
Brand Names Mixture
Antimicina
Chemical_Formula
C19H24N2O3
Antimicina
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Antimicina
fda sheet
Antimicina
msds (material safety sheet)
Antimicina
Synthesis Reference
No information avaliable
Antimicina
Molecular Weight
328.406 g/mol
Antimicina
Melting Point
195-196 oC
Antimicina
H2O Solubility
20 mg/ml (HCl salt)
Antimicina
State
Solid
Antimicina
LogP
2.868
Antimicina
Dosage Forms
Liquid; Tablet
Antimicina
Indication
For the management of hypertension.
Antimicina
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Antimicina
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Antimicina
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Antimicina
Patient Information
Antimicina
Organisms Affected
Humans and other mammals