Pyricidin
Brand names,
Pyricidin
Analogs
Pyricidin
Brand Names Mixture
Pyricidin
Chemical_Formula
C19H24N2O3
Pyricidin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Pyricidin
fda sheet
Pyricidin
msds (material safety sheet)
Pyricidin
Synthesis Reference
No information avaliable
Pyricidin
Molecular Weight
328.406 g/mol
Pyricidin
Melting Point
195-196 oC
Pyricidin
H2O Solubility
20 mg/ml (HCl salt)
Pyricidin
State
Solid
Pyricidin
LogP
2.868
Pyricidin
Dosage Forms
Liquid; Tablet
Pyricidin
Indication
For the management of hypertension.
Pyricidin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Pyricidin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Pyricidin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Pyricidin
Patient Information
Pyricidin
Organisms Affected
Humans and other mammals