Armazid
Brand names,
Armazid
Analogs
Armazid
Brand Names Mixture
Armazid
Chemical_Formula
C19H24N2O3
Armazid
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Armazid
fda sheet
Armazid
msds (material safety sheet)
Armazid
Synthesis Reference
No information avaliable
Armazid
Molecular Weight
328.406 g/mol
Armazid
Melting Point
195-196 oC
Armazid
H2O Solubility
20 mg/ml (HCl salt)
Armazid
State
Solid
Armazid
LogP
2.868
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Dosage Forms
Liquid; Tablet
Armazid
Indication
For the management of hypertension.
Armazid
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Armazid
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Armazid
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Armazid
Patient Information
Armazid
Organisms Affected
Humans and other mammals