Ertuban
Brand names,
Ertuban
Analogs
Ertuban
Brand Names Mixture
Ertuban
Chemical_Formula
C19H24N2O3
Ertuban
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Ertuban
fda sheet
Ertuban
msds (material safety sheet)
Ertuban
Synthesis Reference
No information avaliable
Ertuban
Molecular Weight
328.406 g/mol
Ertuban
Melting Point
195-196 oC
Ertuban
H2O Solubility
20 mg/ml (HCl salt)
Ertuban
State
Solid
Ertuban
LogP
2.868
Ertuban
Dosage Forms
Liquid; Tablet
Ertuban
Indication
For the management of hypertension.
Ertuban
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Ertuban
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Ertuban
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Ertuban
Patient Information
Ertuban
Organisms Affected
Humans and other mammals