Dow-Isoniazid
Brand names,
Dow-Isoniazid
Analogs
Dow-Isoniazid
Brand Names Mixture
Dow-Isoniazid
Chemical_Formula
C19H24N2O3
Dow-Isoniazid
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Dow-Isoniazid
fda sheet
Dow-Isoniazid
msds (material safety sheet)
Dow-Isoniazid
Synthesis Reference
No information avaliable
Dow-Isoniazid
Molecular Weight
328.406 g/mol
Dow-Isoniazid
Melting Point
195-196 oC
Dow-Isoniazid
H2O Solubility
20 mg/ml (HCl salt)
Dow-Isoniazid
State
Solid
Dow-Isoniazid
LogP
2.868
Dow-Isoniazid
Dosage Forms
Liquid; Tablet
Dow-Isoniazid
Indication
For the management of hypertension.
Dow-Isoniazid
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Dow-Isoniazid
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Dow-Isoniazid
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Dow-Isoniazid
Patient Information
Dow-Isoniazid
Organisms Affected
Humans and other mammals