Fimalene
Brand names,
Fimalene
Analogs
Fimalene
Brand Names Mixture
Fimalene
Chemical_Formula
C19H24N2O3
Fimalene
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Fimalene
fda sheet
Fimalene
msds (material safety sheet)
Fimalene
Synthesis Reference
No information avaliable
Fimalene
Molecular Weight
328.406 g/mol
Fimalene
Melting Point
195-196 oC
Fimalene
H2O Solubility
20 mg/ml (HCl salt)
Fimalene
State
Solid
Fimalene
LogP
2.868
Fimalene
Dosage Forms
Liquid; Tablet
Fimalene
Indication
For the management of hypertension.
Fimalene
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Fimalene
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Fimalene
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Fimalene
Patient Information
Fimalene
Organisms Affected
Humans and other mammals